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Updated: Aug 17, 2026

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一个基隙循环探测器介导的双倍放大用于同热检测N6的Methyladenosine修改

Xiaochen Ma1, Yuqing Xia1, Shizheng Wang1

  • 1Department of Chemistry, Faculty of Environment and Life Science, Beijing University of Technology, Beijing 100124, China.

Analytical chemistry
|November 17, 2023
PubMed
概括

研究人员开发了一种新方法,可以精确检测N6-甲基氨酸 (m6A) RNA修饰. 这种超灵敏测试提供了单基分辨率,可以准确地量化细胞中的m6A,有助于诊断疾病.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...