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测试治疗效果异质性的样本大小要求在集群随机试验中的二元结果.

Lara Maleyeff1, Rui Wang1,2, Sebastien Haneuse1

  • 1Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.

Statistics in medicine
|November 17, 2023
PubMed
概括

本研究引入了对集群随机试验 (CRT) 具有二进制结果的新样本大小方法. 这些方法有助于研究人员检测治疗效果异质性,这是强大的临床试验设计的关键步骤.

关键词:
蒙特卡洛方法 蒙特卡洛方法效果的修改影响的修改.一般化的线性混合模型.组随机试验 组随机试验是一个随机试验.集群内部相关系数的相关系数不平等的集群大小不同.

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