老年评估衍生出的赤字累积和患者报告的治疗负担在老年人膀癌
Tullika Garg1, Katie Frank2,3, Alicia Johns2,3
1Department of Urology, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
Journal of the American Geriatrics Society
|November 17, 2023
概括
患有非肌肉侵入性膀癌 (NMIBC) 的老年人经历了较高的脆弱性 (DAI) 和尿路症状 (UDI-6) 报告了显著更大的治疗负担 (TBQ). 需要采取全面的方法来管理衰老和癌症护理负担.
科学领域:
- 老年瘤学 老年瘤学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗保健服务研究 医疗服务研究
背景情况:
- 当医疗需求超过个人资源时,治疗负担就会产生.
- 人们对癌症和衰老的交叉点的治疗负担知之甚少,特别是在膀癌的老年人中.
- 本研究探讨了老年医疗评估工具与这一群体的治疗负担之间的联系.
研究的目的:
- 为了评估赤字积累指数 (DAI) - - 一种衡量虚弱度的指数 - - 与患者报告的治疗负担之间的关联.
- 评估尿路症状 (UDI-6) 与老年人非肌肉侵入性膀癌 (NMIBC) 的治疗负担之间的关系.
主要方法:
- 针对被诊断患有NMIBC的老年人 (≥65岁) 进行了一项横截面调查.
- 逆差积累指数 (DAI) 是使用癌症和衰老研究小组的老年学评估来计算的.
- 患者报告的治疗负担使用治疗负担问卷 (TBQ) 进行测量,尿道症状使用泌尿生殖器应激清单-6 (UDI-6) 进行测量.
- 统计分析包括负二项式回归与LASSO惩罚,以及开放式答案的定性主题内容分析.
主要成果:
- 在119名参与者中,较高的DAI得分与治疗负担增加显著相关 (调整后的IRR为1.94).
- 尿路症状恶化 (UDI-6) 也与更高的治疗负担有显著联系 (调整后的IRR为1.70).
- 患者报告的主要挑战包括癌症治疗,担忧,尿道问题,自我管理和预约安排.
结论:
- 虚弱 (DAI) 和尿路症状 (UDI-6) 都是NMIBC的老年人治疗负担的重要贡献者.
- 这些发现强调了对癌症护理的整体方法的必要性,该方法既解决了与衰老相关的疾病,也解决了癌症治疗的影响.
- 整合老年评估可以帮助识别患有治疗负担风险较高的患者.
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