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评估药剂师对抗癌疗法的双重验证在现代药剂师对抗癌疗法的影响
Devon S Stonerock1, Kaylee Clark2, Vishal Shah3
1Department of Pharmacy, Corewell Health, Grand Rapids, MI, USA.
对抗癌症疗法的第二次药剂师验证 (SPV) 对少量订单有效. 这项研究质疑SPV在现代电子健康系统中的广泛必要性,表明有针对性的应用可能更有效.
科学领域:
- 瘤学 药房 实践
- 药物安全系统 药物安全系统
- 医疗信息学 医疗信息学
背景情况:
- 药剂师订单验证对于患者药物安全至关重要.
- 对抗癌症疗法的第二次药剂师验证 (SPV) 是传统的,但其在电子健康系统中的必要性仍在争论中.
- 证据表明SPV的持续广泛应用是有限的.
研究的目的:
- 评估第二次药剂师验证 (SPV) 流程的持续有效性.
- 为了确定SPV期间进行的抗癌疗法干预的频率.
- 评估SPV发现的变化的临床意义.
主要方法:
- 梅奥诊所需要SPV的抗癌治疗订单的回顾性图表审查 (2019年1月 - 2021年6月).
- 包括住院和门诊的抗癌订单.
- 在初始药剂师验证后进行的订单更改的量化,使用总订单作为分母.
主要成果:
- 在大约30万个订单中,2.6% (N=7634) 在SPV期间需要修改.
- 最常见的变化涉及订单价格,开始时间和药房笔记.
- 显著的剂量变化 (>10%) 仅发生在0.03% (N=99) 的订单中,其中10种特定疗法占其中一半以上.
结论:
- 这项研究是关于SPV影响在现代时代的最大报告.
- 此外,SPV在少量化疗订单的小部分中表现出价值.
- 这些发现引发了关于所有抗癌疗法普遍使用SPV的必要性的问题.
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