更新的评论文章:循环素依赖性激酶4/6抑制剂的影响,FDA批准和抵抗途径

Rodney J Hunter1,2, Jooyoung Park1, Kristen J Asprer2

  • 1Memorial Hermann Texas Medical Center, Houston, TX, USA.

概括

循环素依赖激酶 (CDK) 4/6抑制剂是先进激素受体阳性 (HR+) /HER2-乳腺癌的有效一线治疗方法. 然而,获得的抗药性机制可能会限制治疗的有效性,需要进一步研究以克服这些途径.

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