可转移元素的物种内变异揭示了真菌植物病原体病变型的进化历史上的差异
Anne A Nakamoto1, Pierre M Joubert1, Ksenia V Krasileva1
1Department of Plant and Microbial Biology, University of California, Berkeley, California, USA.
Genome biology and evolution
|November 17, 2023
概括
可转移元素 (TE) 驱动着真菌基因组的进化和变异. 这项研究揭示了Magnaporthe oryzae中的特异性TE扩张和转移,影响了病原体的进化.
科学领域:
- 基因组学就是基因组学.
- 进化生物学 进化生物学
- 菌类学 菌类学是指菌类学.
背景情况:
- 可转移元素 (TE) 是真菌物种内部变异和基因组进化的关键驱动因素.
- 关于TE景观动态及其与真菌种群结构和进化历史的关系的理解有限.
- 由于它们的宿主特异性种群,真菌植物病原体为研究TE多样性提供了有价值的模型.
研究的目的:
- 为了调查TE动态和内容变化在五个谱系的Magnaporthe oryzae,爆发性疾病的致病原体.
- 了解TE扩张的进化历史以及M. oryzae谱系内和之间潜在的水平转移事件.
主要方法:
- 比较基因组学以识别和量化TEs跨不同的M. oryzae血统.
- 遗传学重建,追踪TE扩张的进化历史.
- 对重组模式的分析,以检测潜在的TE转移事件.
主要成果:
- 在M. oryzae族系中观察到TE含量的显著差异.
- 最近特异性TE的谱系特异性扩张,特别是长端重复逆转移,导致了米和塞塔利亚感染谱系中 TE含量更高.
- 发现了米和小麦感染谱系之间最近DNA转子转移的证据,这可能是由同源重组促进的.
结论:
- 在M. oryzae的不同病变型中,TE增殖动态有很大差异.
- TE含量变化提供了关于这个重要的真菌植物病原体的进化历史和适应性的见解.
- 了解TE动态是理解真菌病原体演变的关键.
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