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Updated: Jul 11, 2025

Single-Molecule Förster Resonance Energy Transfer Methods for Real-Time Investigation of the Holliday Junction Resolution by GEN1
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对HOIL-1L和SHARPIN的同位分离的机理性见解

Yan Zhang1, Xiaolong Xu2, Yaru Wang3

  • 1Department of Chemistry, College of Science, Shanghai University, Shanghai, 200444, China; State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.

Biochemical and biophysical research communications
|November 17, 2023
PubMed
概括

HOIL-1L和SHARPIN蛋白通过LTM动图形成二极体,解释了它们的多样化的细胞作用和疾病联系. 这种结构洞察力澄清了突变如何导致多糖体肌肉病变的原因.

关键词:
在HOIL-1L中使用.在 LTM 图案中,使用 LTM 图案.卢巴克 (Lubac) 的一个地方.多葡萄糖体肌肉病变 - 身体肌肉病变利的鱼 (Sharpin) 是一种利的鱼.

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