通过正常怀孕的心血管指数来确定动脉硬度的参考范围
Thanawit Poolsin1, Supatra Sirichotiyakul1, Suchaya Luewan1
1Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
Pregnancy hypertension
|November 17, 2023
概括
这项研究确定了低风险怀孕中动脉硬 (心血管指数) 的参考范围. 这些发现有助于预测怀孕期间的心血管风险.
科学领域:
- 心血管生理学心血管生理学
- 产科和妇科 产科和妇科
- 生物医学工程 生物医学工程
背景情况:
- 在怀孕期间,动脉硬性会增加.
- 心血管指数 (CAVI) 是衡量动脉硬性的指标.
- 在怀孕期间确定CAVI的正常范围对于监测母亲健康至关重要.
研究的目的:
- 确定心脚血管指数 (CAVI) 在低风险孕妇不同妊娠年龄的参考范围.
- 构建妊娠期间平均动脉压 (MAP) 和孕妇心率的参考范围.
- 使用多重回归分析开发CAVI的预测模型.
主要方法:
- 对329名低风险泰国孕妇 (18岁以上,怀孕11-40周) 的横截面研究.
- 排除标准包括妊娠引起的高血压,妊娠期糖尿病和胎儿生长限制.
- 测量包括CAVI,MAP和心率在各种妊娠年龄.
主要成果:
- CAVI显示出与妊娠年龄有显著的相关性 (R2 = 0.049,p < 0.001).
- 母亲年龄与CAVI正相关,而怀孕前的BMI显示出负相关.
- 为正常怀孕建立了MAP和心率的参考范围.
结论:
- 确定了正常怀孕中CAVI的参考范围,作为妊娠年龄的函数.
- 使用多重回归分析开发了CAVI的预测模型.
- 这些参考范围可能有助于识别患心血管疾病风险的孕妇.
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