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艾滋病毒感染者的自杀想法和企图:在2005年至2020年期间,全州人口层面的队列分析

Tianyue Mi¹, Jiajia Zhang², Xueying Yang¹

¹Department of Health Promotion, Education, and Behavior & South Carolina SmartState Center for Healthcare Quality (CHQ), University of South Carolina, Arnold School of Public Health, Columbia, SC.

Journal of acquired immune deficiency syndromes (1999)

|November 17, 2023

概括

随着时间的推移,艾滋病毒感染者 (PWH) 中自杀想法/企图的危险因素发生了变化,精神健康状况在后来的组合抗逆转录病毒疗法 (cART) 时代变得越来越突出. 对于PWH来说,对心理健康的早期发现和干预至关重要.

科学领域:

公共卫生公共卫生
流行病学流行病学
心理健康研究心理健康研究

背景情况:

艾滋病毒感染者 (PWH) 自杀倾向的危险因素在整个疾病进展过程中会发生变化.
随着时间的推移,伴随性疾病,如精神健康障碍,越来越多地影响PWH的自杀风险.

研究的目的:

为了比较不同组合抗逆转录病毒疗法 (cART) 时代的艾滋病毒感染者 (PWH) 自杀想法/企图的主要危险因素.
分析人口统计学,艾滋病毒相关因素和心理健康因素如何预测PWH的自杀倾向.

主要方法:

利用了在2005年至2016年期间诊断的全州PWH队列,并追踪到2020年.
采用考克斯的比例危险模型来评估自杀想法/企图与各种预测因素之间的关联.
检查了人口统计学,艾滋病毒特异性特征和心理健康状况作为潜在的风险因素.

主要成果:

自杀想法/自杀企图的发生率在早期 (2005-2008) 和晚期 (2009-2016) cART时代之间从每10万人年增加了537.7至782.5.
在早期的cART时代,白人种族和双相情感障碍是显著的风险因素.
在cART时代的后期,注射药物使用,焦虑,PTSD,精神分裂症和人格障碍与增加的自杀风险有关.

结论:

在晚期cART时代,心理健康状况是PWH中自杀思想/尝试的越来越重要的风险因素.
更好地获得精神病医疗护理可以帮助早期发现和管理心理健康问题.
及时干预可能会降低PWH中自杀思想/企图的可能性.

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