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Updated: Jul 11, 2025

Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells
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c-Src通过酸化E3结合酶Traf6来调节δ-分泌酶激活和截断的Tau产生

Yanli Jiang1, Longfei Li1, Ruozhen Wu1

  • 1Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

The Journal of biological chemistry
|November 17, 2023
PubMed
概括

这项研究揭示了c-Src如何通过化Traf6来激活阿斯巴拉基尼尔内酶 (AEP),从而导致阿尔茨海默氏症等神经退行性疾病中异常的Tau蛋白积累.

关键词:
在 AEPEP 中,AEPEP 是一个专业组织.阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.美国Src Src陶氏病理学是一种病理学.交通 交通 交通 交通 交通截断 截断是指切断.

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