药物使用的生理影响 药物使用的生理影响
Brian Patrick Murray1, Emily Anne Kiernan2
1Department of Emergency Medicine, Wright State Boonshoft School of Medicine, 2555 University Boulevard, Suite 110, Dayton, OH 45324, USA.
Emergency medicine clinics of North America
|November 17, 2023
概括
本综述详细介绍了常见物质使用的各种生理和心理影响,区分了急性和慢性暴露的影响. 了解这些物质诱导的变化对于有效的医疗干预和患者护理至关重要.
科学领域:
- 药理学和毒理学 药理学和毒理学
- 神经科学是一个神经科学.
- 成 药物 药物 药物 药物
背景情况:
- 药物使用经常导致显著的生理和心理影响.
- 这些影响可以是药物暴露的有意或无意的并发症.
- 由于受体相互作用和同源适应,急性和长期物质暴露往往表现得不同.
研究的目的:
- 综合审查常见物质对生理和心理的影响.
- 阐明导致短期和长期物质变化的机制.
- 提供关于各种滥用药物的影响的综合资源.
主要方法:
- 对同行评审文章的文献评论.
- 综合有关乙醇,镇静催眠药,兴奋剂,大麻,阿片类药物,尼古丁,碳化合物和氧化的影响的数据.
- 分析受体介导作用和恒常性变化的分析.
主要成果:
- 对每个物质类别的生理和心理影响的详细描述.
- 识别不同的急性和慢性暴露档案.
- 解释涉及物质效应的神经生物学途径.
结论:
- 吸毒对身体和心理产生广泛的影响.
- 药物的影响因药物,剂量,持续时间和个人因素而异.
- 这份综述强调了物质使用障碍及其管理的复杂性.
相关概念视频
Substance Use Disorders Affecting Sleep
173
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
173
Drug Dependence
1.0K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.0K
CNS Depressants: Alcohol and Nicotine
216
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
216
Drug Abuse and Addiction: Pharmacological Phenomena
487
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
487
An Overview of Psychoactive Drugs
235
Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
235
Effects of Chemicals: Overview
1.3K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
1.3K


