治疗耐药性尿泡症治疗反应的预测因素
Ida Uhrenius1, Amadeus Bergsten1, Tryggve Nevéus2
1Department of Women's and Children's Health, Uppsala University, Sweden.
Journal of pediatric urology
|November 17, 2023
概括
虚空图表无法预测患有持续尿尿症 (尿床) 的儿童的治疗成功. 这项研究质疑它们的常规使用,因为它们可能会延迟对尿性儿童的基本护理.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 临床实践评估 临床实践评估
背景情况:
- 排空图是评估尿尿症的标准工具,但其对治疗反应的预测价值仍在争论中.
- 之前的试点研究表明,空白图表数据无法预测对尿二线治疗的反应.
研究的目的:
- 评估历史记录和空白图表数据是否预测了治疗耐药性尿道症儿童的治疗反应.
- 复制以前的发现关于空白图的有限预测价值.
主要方法:
- 一项临床实践评估包括了70名对一线治疗有抗性尿液浸泡症的患者.
- 收集的数据包括基线膀和肠道习惯以及通过排泄图表的夜间尿液产量.
- 患者接受了第二线和第三线治疗,包括抗胆固醇药,抗抑郁药,以及根据需要的desmopressin.
主要成果:
- 在70名患者中,有37名患者实现了干燥;11名患者保持了失 incontinence,22名患者在随访中失去了.
- 对抗胆固醇药物,抗抑郁药物,警报重试和自发解决的治疗成功.
- 只有较硬和较少的便与抗胆固醇药物的反应有显著的关联.
结论:
- 历史记录和空白图表数据不能预测治疗耐药尿液浸泡症儿童的治疗反应.
- 在评估耐治疗性尿尿失禁时,空白图的常规使用受到质疑,原因是缺乏预测价值和可能的护理延迟.
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