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Updated: Jul 10, 2025

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血液恶性瘤的诊断工作与潜在的生殖线倾向性疾病 (GPD)

Rashmi Kanagal-Shamanna1, Kristian T Schafernak2, Katherine R Calvo3

  • 1Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Seminars in diagnostic pathology
|November 17, 2023
PubMed
概括

生殖线倾向性疾病增加了血液性恶性瘤的风险. 本综述详细介绍了诊断工作,重点关注骨髓形态学和这些疾病中的遗传变化.

关键词:
在AML,AML就是AML.DDX41 DDX41 在线播放在 GATA2 中.生殖线倾向于发生骨髓性恶性瘤.在 MDS MDS 中.在RUNX1中,使用RUNX1.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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