使用增材制造和有限元分析进行机械刚性的表征:用于骨健康评估的潜在工具
Sriharsha Marupudi1, Qian Cao2, Ravi Samala1
1Division of Imaging, Diagnostics, and Software Reliability, Office of Science and Engineering Labs, U.S. Food and Drug Administration, Silver Spring, MD, USA.
3D printing in medicine
|November 17, 2023
概括
机械测试和微有限元素分析 (μFEA) 显示出对评估骨硬度的良好一致. 这在骨健康研究中验证了用于微细元素分析 (μFEA) 的3D打印幻影.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 整形外科 整形外科 整形外科
背景情况:
- 骨硬度对于骨健康和骨折风险评估至关重要.
- 微有限元素分析 (μFEA) 和3D打印幻象的机械测试是估计骨机械性能的方法.
- 幽灵的μFEA和机械测试之间的一致性需要验证.
研究的目的:
- 为了评估机械测试的刚度测量与3D打印的脊椎骨幻象的μFEA之间的一致性.
- 确定3D打印是否是验证骨结构μFEA模型的可行方法.
主要方法:
- 从腰椎骨中使用选择性激光烧结创建了轨道骨幻影.
- 幻影进行了机械测试 (无轴压缩) 和in silico μFEA模拟.
- 布兰德-阿尔特曼分析评估了一致性;虚幻保真性和过程重复性也得到了评估.
主要成果:
- 在机械测试硬度和μFEA硬度之间发现了良好的一致性 (R2=0.84).
- 3D打印的幻影表现出高结构保真度 (子分数=0.97) 和机械测试是可重复的 (CV<5%).
- 幻影中的微观结构缺陷可能解释了刚度值的轻微差异.
结论:
- 该协议支持使用μFEA来评估复杂的椎结构中的骨力学.
- 这证实了3D打印幻象在骨健康分析中用于μFEA模型验证的使用.
- 这些发现有助于对骨健康和骨折风险进行可靠的非侵入性评估.
相关概念视频
Bending of Members Made of Several Materials
In analyzing a structural member composed of two different materials with identical cross-sectional areas, it is crucial to understand how their distinct elastic properties affect the member's response under load. The analysis involves assessing stress and strain distributions using the transformed section concept, which accounts for variations in material properties.
Hooke's Law determines stress in each material, stating that stress is proportional to strain but varies due to each material's...
Hooke's Law determines stress in each material, stating that stress is proportional to strain but varies due to each material's...
Yield Criteria for Ductile Materials under Plane Stress
In designing structural elements and machine parts using ductile materials, it is crucial to ensure that these components withstand applied stresses without yielding. Yielding is initially determined through a tensile test, which evaluates the material's response to uniaxial stress. However, tensile stress is insufficient when components face biaxial or plane stress conditions This condition requires advanced criteria to predict failure.
The Maximum Shearing Stress Criterion, also known as the...
The Maximum Shearing Stress Criterion, also known as the...


