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Updated: Jul 10, 2025

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes
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目标依赖RNA聚合酶作为对细胞内分子反应的基因表达控制的通用平台

Shodai Komatsu1,2, Hirohisa Ohno1, Hirohide Saito3,4

  • 1Department of Life Science Frontiers, Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

Nature communications
|November 17, 2023
PubMed
概括

我们开发了一种依赖目标的RNA聚合酶 (TdRNAP) 用于使用更广泛的分子来控制基因表达. 这种新的工具可以精确控制生物工程和治疗应用.

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