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Updated: Jul 10, 2025

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SEPTIN2抑制了一种独立于IFN-γ的,促炎性巨细胞激活通路

Beibei Fu1, Yan Xiong1, Zhou Sha1

  • 1School of Life Sciences, Chongqing University, 401331, Chongqing, China.

Nature communications
|November 17, 2023
PubMed
概括

SEPTIN2 (SEPT2) 负面调节了独立于干扰素 (IFN-γ) 的巨细胞自身激活. 这一途径涉及内质网膜 (ER) 应激,平衡蛋白质修饰以控制炎症并防止组织损伤.

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