在低剂量胸部计算机断层扫描中,吸烟和胸部骨肌肉不成比例的变化
Woo Hyeon Lim1, Suhyun Jeong2, Chang Min Park3,4,5,6
1Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
吸烟强度对胸部骨肌 (TSM) 的数量和质量产生负面影响,特别是在上部和中部区域. 这项研究量化了吸烟.
科学领域:
- 放射学和胸部成像技术
- 骨肌肉生理学 骨肌肉生理学
- 肺部病理学 肺部病理学
背景情况:
- 吸烟是一个主要的公共卫生问题,已知有系统性影响.
- 吸烟强度对胸部骨肌 (TSM) 量和质量的影响尚不清楚.
- 了解这些影响对于评估吸烟者的整体健康和疾病风险至关重要.
研究的目的:
- 研究吸烟强度与男性各种胸部骨肌肉 (TSM) 的数量和质量之间的关联.
- 为了确定特定的TSM地点是否比其他地方受吸烟强度的影响更大.
主要方法:
- 定量CT分析用于测量骨肌肉指数 (SMI) 的肌肉数量和正常衰减肌肉面积 (NAMA%) 的比例,以测量肌肉质量.
- 测量了大动脉门的胸部肌肉 (AA-PM),大动脉门的TSM (C-TSM),T12 (T12-ESM) 的直立脊柱肌肉和L1 (L1-SM) 的骨肌肉.
- 统计分析评估了吸烟强度 (包年) 与TSM,SMI和NAMA%之间的相关性.
主要成果:
- 吸烟强度与上胸部区域 (AA-PM) 中SMI和NAMA%的下降显著相关.
- 更高的吸烟强度与中胸部区域 (C-TSM) 的较低NAMA%相关,与SMI的边界关联.
- 吸烟强度影响了下胸部区域 (L1-SM) 的NAMA%,但没有SMI,与T12-ESM的数量或质量没有显著的关联.
结论:
- 吸烟强度与胸部骨肌肉 (TSM) 的数量和质量降低有关.
- 吸烟的影响因TSM位置而异,上部 (AA-PM) 和中部 (C-TSM) 区域显示最显著的关联.
- 这些发现强调了吸烟对胸肌健康的有害影响,可能对患者的评估和治疗产生影响.
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