负面情绪减少了奖励结果在腹中介前额叶皮层的可分辨性
Lakshman N C Chakravarthula1, Srikanth Padmala1
1Centre for Neuroscience, Indian Institute of Science, Bangalore, KA 560012, India.
Social cognitive and affective neuroscience
|November 18, 2023
概括
负面情绪会损害大脑区分奖励和无奖励结果的能力,特别是在腹中前额叶皮层 (vmPFC). 这一发现揭示了情绪如何影响奖励处理.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 情感神经科学是一种神经科学.
背景情况:
- 情绪和奖励处理在人类大脑中是密切相关的.
- 了解这些相互作用,特别是在奖励消费期间,至关重要但有限.
- 现有的研究往往忽视了负面情绪对奖励结果评估的影响.
研究的目的:
- 为了研究负面情绪如何影响大脑的奖励结果处理.
- 探索由情感价值来调节奖励的基础的神经机制.
- 检查特定大脑区域的作用,如vmPFC,腹状条纹体和杏仁体.
主要方法:
- 用一种新的实验设计进行功能磁共振成像 (fMRI) 研究.
- 参与者完成了一个选择任务,其中情感价值标志着结果类型 (奖励/无奖励).
- 多声元模式分析 (MVPA) 应用于预定义感兴趣区域的fMRI数据.
主要成果:
- 在腹中介前额叶皮质 (vmPFC) 中,负面情绪线索降低了大脑区分奖励和无奖励结果的能力.
- 解码分析显示,活动模式的区分能力降低,与负面图像与中性图像标志着的结果相关.
- 有证据表明,在一个共同的价值/价值维度上,奖励处理的情感调节.
结论:
- 负面情绪显著调节人类大脑中的奖励结果处理.
- 研究结果强调了负面影响对奖励价值的神经表征的影响.
- 这些见解对理解心理健康状况如焦虑和抑郁有潜在的影响.
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