晚期肺癌炎症指数与老年营养风险指数相结合,预测心力衰竭患者的全因死亡率
Tao Shi1, Yan Wang1, Yunzhu Peng1
1The First Affiliated Hospital of Kunming Medical University, Kunming, China.
BMC cardiovascular disorders
|November 18, 2023
概括
晚期肺癌炎症指数 (ALI) 和老年营养风险指数 (GNRI) 预测心力衰竭 (HF) 患者的死亡率. 结合ALI和GNRI为HF患者的治疗结果提供了宝贵的预后见解.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 炎症生物标志物 炎症生物标志物
背景情况:
- 心力衰竭 (HF) 是一个重大的全球健康挑战.
- 确定可靠的预后标志物对于HF患者是改善临床管理的关键.
- 晚期肺癌炎症指数 (ALI) 和老年营养风险指数 (GNRI) 是患者健康状况的潜在指标.
研究的目的:
- 调查晚期肺癌炎症指数 (ALI) 和老年营养风险指数 (GNRI) 对被诊断为心力衰竭 (HF) 患者全因死亡率的预测能力.
主要方法:
- 分析了1123名HF患者的队列.
- 根据中位数ALI和GNRI值,患者被分为四组.
- 使用卡普兰-梅尔分析和多变量考克斯比例危险模型来评估死亡风险.
主要成果:
- 在ALI和GNRI之间观察到轻微的正线性相关性 (r=0.348,p<0.001).
- ALI和GNRI都被确定为HF患者全因死亡率的独立预测因素 (p<0.001).
- ALI和GNRI的联合AUC为0.711,这表明预测性能良好.
结论:
- 晚期肺癌炎症指数 (ALI) 和老年营养风险指数 (GNRI) 是心力衰竭患者全因死亡率的独立预测指标.
- ALI (<24.60) 和GNRI (<94.41) 的组合识别出HF患者的死亡风险最高.
- 综合使用ALI和GNRI证明了对心力衰竭预后的显著预测价值.
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