我如何治疗妊娠中状细胞疾病
Andra H James1,2, John Joseph Strouse2,3
1Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, Duke University, Durham, NC.
Blood
|November 18, 2023
概括
现在鼓励状细胞疾病 (SCD) 妇女怀孕,但需要谨慎管理. 对孕产妇和胎儿并发症的认识对于SCD怀孕的最佳结果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 血液学 血液学 血液学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 从历史上看,对于患有状细胞病 (SCD) 的人来说,不建议怀孕.
- 目前的医学理解支持大多数SCD患者怀孕.
- 怀孕期间的生理变化可以加剧SCD,带来独特的挑战.
研究的目的:
- 为患有SCD的患者及其医疗保健提供者提供有关怀孕风险和管理的信息.
- 为了突出怀孕期间与SCD相关的孕产妇和胎儿并发症.
主要方法:
- 关于SCD和怀孕的现有文献和临床指南的审查.
- 识别常见的孕产妇和胎儿并发症.
- 强调多学科的护理方法.
主要成果:
- 在SCD中怀孕可能导致母亲的并发症,包括器官功能障碍,血管闭塞危机,急性胸部综合征,孕前,败血症和血栓栓塞.
- 胎儿并发症包括非免疫接种,阿片类药物暴露,生长限制,早产和死产.
- 剖腹产可能会更频繁.
结论:
- 怀孕现在被认为是大多数SCD患者的可行选择.
- 在怀孕前和怀孕期间,全面的评估和多学科的团队管理是至关重要的.
- 积极管理SCD特异性和与怀孕相关的风险对于母亲和胎儿的健康至关重要.
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