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在LA-ICP-MS映射中,利用废弃量进行校准,以解决矩阵内和矩阵之间废弃率的变化

Kristina Mervič¹, Johannes T van Elteren¹, Marjan Bele²

¹Department of Analytical Chemistry, National Institute of Chemistry, Hajdrihova 19, Ljubljana, 1000, Slovenia.

|November 18, 2023

概括

使用激光切除感应合等离子体质谱法 (LA-ICP-MS) 绘制精确的元素量化需要对切除速率差异进行校正. 本研究引入了使用光学造型测量进行更精确的元素度测量的体积校正方法.

科学领域:

地质化学地质化学
分析化学分析化学
材料科学材料科学材料科学

背景情况:

在2D LA-ICP-MS映射中,矩阵匹配标准和内部标准化是常见的.
内部标准的均分布和统一的激光吸收率是关键的,但往往是未满足的要求.
现有的方法与元素分数和仪器漂移作斗争,影响量化准确性.

研究的目的:

开发和验证一种新的方法来纠正二维LA-ICP-MS映射中的剥离率差异.
提高元素度量化的准确性,特别是在异质样本中.
从以质量为基础的度单位转移到以体积为基础的度单位,以提高可比性.

主要方法:

使用光学分析仪来测量每个像素的剥离体积.
根据测量的消去体积,规范化元素图.
对不同元素度的装饰玻璃 (murrina) 样本进行体积校正.

主要成果:

废除体积辅助校准显著提高了2DLA-ICP-MS地图中的元素度的准确性.
该研究表明,对于装饰玻璃等异质材料,更可靠的量化方法.
质量/体积度 (μg cm−3) 被提出为比质量/体积 (μg g−1) 更强大的单位.

结论:

样品和标准之间的剥离率的变化,如果不纠正,可能导致元素度不准确.
基于光学分析的体积校正为LA-ICP-MS量化提供了更准确的方法.
一般的校准协议可能会失败,当剥离率显著不同时,突出需要先进的校正方法.

关键词:

在LA-ICP-MS中使用.激光切除术是一种激光切除术.绘制地图是为了绘制地图.通过光学造型测量,可以测量光学造型.这就是SEM-EDXX.

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