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对更年期相关症状和脑皮质活动在更年期的fNIRS调查

Yang Zhou¹, Jiawen Lin², Changbin Li¹

¹Department of Gynecology and Obstetrics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, People's Republic of China.

Journal of affective disorders

|November 18, 2023

概括

更年期症状和更长的更年期持续时间与降低前额前脑活动有关. 超重也与绝经后妇女的叶下部活动有关,突出显示需要对大脑健康进行监测.

科学领域:

神经科学是一个神经科学.
妇女健康妇女健康
绝经研究绝经研究

背景情况:

更年期显著影响女性的健康,并可能带来神经系统的后果.
了解更年期症状与大脑功能之间的关系对于老年女性至关重要.

研究的目的:

为了研究更年期症状与大脑皮层血动力学之间的关联.
为了确定影响大脑血液动力学反应的因素,在近期和绝经后的妇女.

主要方法:

对358名汉族妇女进行了跨度剖析研究,这些妇女年龄在更年期前后.
使用库珀曼指数 (KMI) 和PSQI尺度评估的更年期症状.
通过功能近红外光谱学 (fNIRS) 测量的大脑血液流量;用多重线性回归分析.

主要成果:

更年期症状和更长的更年期持续时间与下部前额叶血液动力学反应相关.
超重 (BMI ≥24 kg/m2) 与叶皮质活动减少有关.
经过调整以考虑混因素后,关联仍然很重要.

结论:

更年期症状和超重是影响更年期后妇女大脑健康的重要因素.
这些发现支持早期检测和干预策略,包括更年期激素治疗 (MHT).
强调监测经历更年期的老年妇女的大脑健康的重要性.

关键词:

更年期的症状是更年期的症状.更年期绝经绝经体重过重的情况前额叶皮层前额叶皮层.时间皮层时间皮层在FNIRS中使用.

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