在非慢性病患者群体中,酸产品与冠状动脉全封闭之间的关系:一项横截面研究
Kaiyong Xiao1, Huili Cao2, Liang Liu1
1The Second Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, China.
The American journal of cardiology
|November 18, 2023
概括
在没有慢性病 (CKD) 的个体中,较高的产品 (Ca-P产品) 与冠状动脉完全封闭 (TCAO) 的风险降低有关. 保持Ca-P产品低于27.46 mg2/dl2可能有助于预防TCAO.
科学领域:
- 心血管医学 心血管医学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 生物化学 生物化学
背景情况:
- 产品 (Ca-P产品) 的升高与慢性病 (CKD) 患者的心血管问题有关.
- 在非CKD人群中,Ca-P产品与冠状动脉疾病之间的关联仍未得到充分研究.
研究的目的:
- 调查Ca-P产品在非CKD人群中冠状动脉全封闭 (TCAO) 的作用.
- 为了确定与TCAO风险相关的Ca-P产品在这个人口群体中的值.
主要方法:
- 一项涉及983名接受冠状动脉血管造影的患者的横截面研究.
- 作为连续变量和三级变量计算和分析的Ca-P产物.
- 后勤回归和受限制的立方线用于统计分析.
主要成果:
- 在Ca-P产品和TCAO风险之间发现了显著的反向关联 (或每单位增加0.96).
- 高Ca-P产品组显示,与最低组相比,TCAO的风险降低了40%.
- 观察到一种非线性关系,在27.46 mg2/dl2的Ca-P产品后,TCAO风险显著下降2.2.
结论:
- 在非CKD人群中,较高的Ca-P产物 (≥27.46 mg2/dl2) 与较低的TCAO风险有关.
- 这一发现表明,高的Ca-P产品在没有脏疾病的个体中可能有保护作用,防止冠状动脉完全堵塞.
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