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患有心房动的患者视网膜微血管功能受损

Valentina A Rossi¹, Natallia Laptseva¹, Delia Nebunu¹

¹University Heart Center, University Hospital of Zurich, Switzerland.

International journal of cardiology

|November 18, 2023

概括

心房动 (AF) 与心力衰竭患者视网膜微血管功能受损有关. 这种血管功能障碍与较大的左心房体积有关,这表明心脏压力和血管健康之间存在联系.

科学领域:

眼科医生眼科眼科
心脏病学心脏病学
血管生物学血管生物学

背景情况:

心血管疾病,特别是心力衰竭,与视网膜微血管内皮功能不佳有关.
心房 (AF) 对血管功能障碍的具体贡献尚不清楚.

研究的目的:

为了研究心房 (AF) 对视网膜微血管功能的影响.

主要方法:

使用闪光诱导的视网膜动脉的血管扩张 (FIDart%) 非侵入性评估了血管功能.
患有AF和心力衰竭史的患者 (n=69) 与没有AF (n=66) 的匹配对照进行了比较.
AF患者根据节奏分组 (鼻节奏与访问期间的AF).

主要成果:

与没有AF的患者相比,视网膜微血管功能显著受损 (FIDart% 1.1%对2.7%,p < 0.001).
访问期间的AF患者表现得比AF病史但在鼻节律中的患者差 (FIDart% 0.8%对1.5%,p = 0.017).
在AF患者中,视网膜血管功能受损与左心房体积较大独立相关 (p = 0.01-0.035).

结论:

在心力衰竭患者中,心房动 (AF) 与血管功能受损有关,无论当前的心律如何.
视网膜微血管功能障碍和左心房体积之间的联系表明心脏填充压力升高和AF发展中的血管健康之间的相互作用.

关键词:

心房动是一种心房动.脑内皮的功能脑内皮功能通过流介导的扩张.视网膜血管功能视网膜血管功能

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