在SARS-CoV-2感染后的运动能力与军事人员心血管和肺功能变化有关
Rebecca R Chamley1, Jennifer L Holland2, Jonathan Collins3
1University of Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, Oxford, United Kingdom; Defence COVID-19 Recovery Service, Stanford Hall, Loughborough, UK; Academic Department of Military Medicine, Birmingham, UK; Royal Centre for Defence Medicine (South), Oxford, UK.
军事人员的后COVID综合征与运动能力降低和亚临床心脏和肺部变化有关. 区分COVID-19的影响与脱水是恢复的关键.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 运动医学 运动医学
- 军人卫生保健 军人卫生保健
背景情况:
- 后COVID综合征带来了持续的医疗和经济挑战,特别是对于需要达到体能峰值的军事人员来说.
- 长时间的症状会影响军事部署,留守和心理健康.
- 有限的研究存在于后COVID综合征对军事人口的运动能力和心肺功能的影响.
研究的目的:
- 调查英国军人中后COVID综合征的运动能力和心肺影响.
- 为了在不同COVID-19严重程度组和健康对照中比较这些影响.
主要方法:
- 招募英国军事人员分为三个组:健康对照组,轻度中度COVID-19幸存者和严重的COVID-19幸存者.
- 使用心脏磁共振成像 (CMR) 和光谱,心声学,肺功能测试和心肺运动测试 (CPET).
主要成果:
- 观察到峰值工作,VT1,VO2max,FVC,FEV1,TLC,VA和DLCO的逐步下降,随着COVID-19严重程度的增加.
- 记录了A-a梯度的逐步增加和LV/RV体积,冲程体积和LV质量的减少.
- CPET,肺功能和CMR揭示了与后COVID综合征相关的显著亚临床变化.
结论:
- 现役军事人员的后COVID综合征与最大运动能力的亚临床减少有关.
- 研究结果表明,除了COVID-19特定变化之外,还存在一种脱条件的表型.
- 在康复过程中,区分病理性COVID-19后果和脱离条件仍然是一个挑战.
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