相关实验视频

Updated: Jul 10, 2025

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
08:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

14.7K

Brca1鼠标模型:功能洞察力和治疗机会

Wei-Ting Yueh1, David J Glass1, Neil Johnson1

  • 1Nuclear Dynamics Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

Journal of molecular biology
|November 18, 2023
PubMed
概括

工程Brca1小鼠模型有助于了解DNA修复和癌症. 这些自20世纪90年代以来开发的模型对于研究Brca1蛋白功能和改善抗癌疗法至关重要.

关键词:
这就是 Brca1 的意思.修复DNA的修复DNA的修复同类的重组组合.鼠标模型 鼠标模型

更多相关视频

Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland06:29

Modeling Breast Cancer via an Intraductal Injection of Cre-expressing Adenovirus into the Mouse Mammary Gland

Published on: June 7, 2019

12.8K
Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer07:45

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer

Published on: May 18, 2020

6.1K

相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.6K