胃食道逆流的研究. 在肥胖患者的功能测试的解释
Elizabeth Barba Orozco1, Alberto Ezquerra Duran1
1Gastroenterology Department, Neurogastroenterology and Motility Unit, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.
Cirugia espanola
|November 18, 2023
概括
肥胖会增加胃食道逆流性疾病 (GERD) 的症状,尤其是在夜间. 这篇评论讨论了功能测试,如食道测量和pH阻抗测量,用于诊断GERD和运动障碍.
科学领域:
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
- 消化系统疾病 消化系统疾病
背景情况:
- 肥胖是世界卫生组织认可的全球流行病,影响了欧洲人口的很大一部分.
- 胃食道逆流性疾病 (GERD) 的患病率在超重和肥胖个体中明显较高.
- 肥胖与GERD症状的增加有关,特别是夜间反流和酸暴露.
研究的目的:
- 审查用于诊断GERD和食道运动障碍的功能测试的解释.
- 为了突出肥胖,GERD症状和夜间反流之间的相关性.
- 讨论侵蚀性食道炎和非侵蚀性反流性疾病 (NERD) 的诊断方法.
主要方法:
- 对包括消化内镜,24小时pH监测和24小时pH阻抗计在内的诊断工具的审查.
- 讨论食道测量仪用于评估食道运动性.
- 对反流监测研究的分析,以确定病态酸暴露.
主要成果:
- 消化内镜检测到侵蚀性食道炎在50%的症状患者.
- 在92%的患者中,24小时pH阻抗计诊断出NERD.
- 肥胖患者在夜间反流更频繁,酸性反流发作增加.
结论:
- 持续的GERD可能导致无效的食道运动障碍.
- 准确的解读力度和反流监测对于管理GERD至关重要.
- 功能测试对于诊断肥胖患者的GERD和相关的运动问题至关重要.
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