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儿科患者肝转移切除术:一项观察性研究

Andrew M Fleming¹, Sara A Mansfield¹, Tim Jancelewicz¹

¹St. Jude Children's Research Hospital, Department of Surgery, Memphis, TN, USA; The University of Tennessee Health Science Center, Department of Surgery, Memphis, TN, USA.

Journal of pediatric surgery

|November 18, 2023

概括

在患有转移性疾病的儿童中,肝转移切除术是安全有效的,可能引导治疗并改善长期存活率. 这项研究强调了它在特定儿科病例中的有用性.

科学领域:

儿科瘤学儿科瘤学
手术瘤学手术瘤学
肝脏手术肝脏手术

背景情况:

肝切除术对儿科转移性疾病的作用受到争论.
潜在的益处包括治疗,诊断和化疗指导.
这项研究评估了肝转移切除术在儿童中的安全性和效用.

研究的目的:

评估肝转移切除术在儿科患者中的安全性和效用.
确定转移切除术对辅助治疗决策的影响.
分析儿童肝转移切除术后的生存结果.

主要方法:

对接受肝转移切除术的儿童医疗记录 (1995-2022) 的回顾性审查.
在初级瘤切除过程中排除封锁性肝切除术.
收集关于患者人口统计,瘤特征,手术程序和结果的数据.

主要成果:

16名儿科患者因各种组织学原因接受了肝转移切除术.
没有观察到Clavien-Dindo III级或更高的外科手术期间发病率.
疾病特异性10年生存率为77%,无疾病生存率为61%.

结论:

肝转移切除术在儿科患者中是一种安全的手术.
转移切除术可以为辅助治疗决策提供信息.
该程序与选择儿童的有利的长期存活有关.

关键词:

细菌细胞瘤的发生.肝脏转移的发生.神经母细胞瘤是一种神经母细胞瘤.威尔姆斯瘤是一种瘤.

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