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家庭主体转录调节器DVE-1在电路改造期间指导一个用于突触消除的程序

Kellianne D Alexander1,2, Shankar Ramachandran1, Kasturi Biswas1,2

  • 1Department of Neurobiology, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Nature communications
|November 18, 2023
PubMed
概括

转录调节器DVE-1指导在发育中的C. elegans神经元中突触消除. 这一过程对大脑成熟至关重要,涉及到无素-蛋白酶体系统,突出显示了SATB家族成员在神经回路改造中的作用.

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