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Updated: Jul 10, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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Published on: August 20, 2019

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在INTS11中,一种同卵性变体将线粒分裂和神经发生缺陷与严重的神经发育障碍联系起来

Hanzhe Kuang1, Yunlong Li1, Yixuan Wang1

  • 1Center for Medical Genetics, Hunan Key Laboratory of Medical Genetics, MOE Key Lab of Rare Pediatric Diseases, School of Life Sciences, Central South University, Changsha 410000, China.

Cell reports
|November 19, 2023
PubMed
概括

一项新的研究表明,INTS11基因的突变会通过损害细胞分裂和神经发育,导致严重的神经发育障碍 (NDD). 这项研究为研究NDD提供了一个新的细胞模型.

关键词:
科普:神经科学是什么意思科普:干细胞研究在INTS11中,我们可以使用INTS11.整合器复杂的整合器.发生线粒分裂 (mitosis).神经发育障碍是一种神经发育障碍.神经发生神经发生.

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