在一个极度早产的婴儿中,晚发的维生素K缺乏症出血,该婴儿被养以纯母乳为基础的饮食
Vimal Vasu1, Shaveta Mulla2, Atisha Pandya2
1Department of Neonatal Medicine, William Harvey Hospital, Ashford, Kent, UK; School of Biosciences, University of Kent, Canterbury, UK.
Journal of thrombosis and haemostasis : JTH
|November 19, 2023
概括
那些以母乳为基础的强化剂强化母乳饮食的极度早产婴儿可能面临维生素K缺乏症出血 (VKDB) 的风险. 这一案例凸显了需要评估这些脆弱婴儿的维生素K1摄入量.
科学领域:
- 新生儿科学 新生儿科学
- 营养科学 营养科学
- 儿科胃肠病学 儿科胃肠病学
背景情况:
- 所有新生儿都需要基 (维生素K1) 来预防维生素K缺乏症出血 (VKDB).
- 过早出生的婴儿,特别是那些只食用母乳的婴儿,面临着由于可能不足的K1摄入量而出现晚期VKDB的风险.
- 基于人乳的强化剂 (HMF),虽然对微量营养素有好处,但与来自牛的强化剂相比,它们含有较低的K1水平.
研究的目的:
- 报告一个晚发的VKDB病例,该病例发生在一个极度早产的婴儿身上,该婴儿仅用HMF.母乳养.
- 量化该婴儿在出血事件之前的维生素K1总摄入量.
主要方法:
- 一个极其早产婴儿的案例报告.
- 从预防性管理,亲肠道和肠道料中量化维生素K1摄入量,包括HMF.
主要成果:
- 婴儿经历了晚期发病的VKDB,尽管接受了纯母乳饮食,并补充了HMF.
- 分析显示出出血之前的维生素K1总摄入量.
结论:
- 强化HMF的纯母乳养可能无法提供足够的维生素K1来预防极早产婴儿晚期发病的VKDB.
- 需要对维生素K1的需求和HMF的早产婴儿的最佳强化策略进行进一步的研究.
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