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在先天性完整心脏阻塞中放置起器之前和之后的纵向心声学参数

Scott J Weinreb¹, Steve B Ampah², Oluwatimilehin Okunowo³

¹Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

|November 19, 2023

概括

心脏起器有助于使先天性完全心脏阻塞 (CCHB) 的儿童的左心室大小正常化. 鼓动后,左心室喷射率 (LVEF) 等心声学参数在长期内保持在正常范围内.

科学领域:

儿童心脏病学儿童心脏病学
心脏电生理学心脏电生理学
遗传性心脏病是一种先天性心脏病.

背景情况:

先天性完全心脏阻塞 (CCHB) 影响1:15,000-1:20,000活产.
CCHB具有7%-23%的左心室 (LV) 功能障碍或扩张性心肌病的风险.

研究的目的:

分析节奏CCHB患者的LV大小和缩功能的连续变化.
评估心脏起器植入后时间对心声回声学参数的影响.

主要方法:

对52名节奏CCHB受试者的回顾性队列分析,带有节奏器前后心脏回声图数据.
线性混合效应回归建模的LV终端透析维度 (LVEDD) z-score,LVSF,和LVEF.
放心器安置前后回声心脏学参数斜率的比较.

主要成果:

估计的LVEDDz-score在心脏起器安置后显著下降 (-0.08每年).
估计LV缩短分数 (LVSF) 在节拍前降低,但在节拍后稳定.
在心脏起器后的15年内,LV喷射分数 (LVEF) 保持稳定,在正常范围内.

结论:

心脏起器植入导致CCHB患者的LV尺寸显著改善.
节奏的CCHB受试者长期保持正常的LVSF和LVEF,这表明有效的血液动力学支持.

关键词:

节律失常 (arrhythmia) 是一种心律失常.原始的完整的心脏阻塞.扩展性心肌病变性是指扩展性心肌病变性心声回声扫描 (Echocardiography) 是一种心声回声扫描.左心室的功能是没有的.起器是一种心脏起器.心脏起器诱导的心肌病变.

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