与腹膜透析相关的耐火性腹膜炎是由Enterococcus gallinarum引起的
Kaho Yamasaki1, Seiko Ishikawa1, Takefumi Suzuki1
1Department of Nephrology and Hypertension, Tokyo Kyosai Hospital, Japan.
Internal medicine (Tokyo, Japan)
|November 19, 2023
概括
在腹膜透析患者中,一种罕见的抗万科米辛的Enterococcus gallinarum腹膜炎的病例被成功地用导管切除和安比西林治疗. 这凸显了在透析患者中管理耐药感染的挑战.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 腹膜炎是经过腹膜透析 (PD) 的患者的严重并发症.
- 肠球菌种类是腹膜炎的不常见原因,而万科米辛耐药性对治疗提出了重大挑战.
- 这个病例涉及一个患有PD病史和状炎的患者,使临床情况复杂化.
研究的目的:
- 在PD患者中报告一种罕见的抗万科素的Enterococcus gallinarum外周炎病例.
- 讨论所遇到的诊断和治疗挑战.
- 强调导管切除对于耐火病例治疗成功的重要性.
主要方法:
- 一个65岁的女性患者的临床病例介绍.
- 腹腔内液和血液培养物的分析,用于微生物鉴定.
- 用于指导治疗的抗微生物敏感性测试.
- 对治疗修改和患者结果的审查.
主要成果:
- 鉴定出Enterococcus gallinarum是血液和腹腔内排泄物中腹腔炎的致病原体.
- 隔离物体表现出万科米辛耐药性,需要使用替代抗生素策略.
- 最初的经验性治疗以美罗和随后的万科米辛是无效的,导致腹膜炎恶化.
- 用安培林治疗和最终切除腹膜透析导管导致患者完全康复.
结论:
- 胆杆菌 (Enterococcus gallinarum) 是一种罕见但显著的导致PD患者患上万科胺素耐药性周周炎的病因.
- 管理需要仔细考虑抗菌素耐药性模式,可能需要取出导管以治愈.
- 这一案例强调了及时诊断和在PD相关的周周炎中量身定制的抗生素治疗的重要性.
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