小到中度儿科烧伤的流行病学和早期细菌殖民:来自发展中国家的回顾性研究
Zlatan Zvizdic1, Lamija Hukic2, Amela Dedeic Ljubovic3
1Clinic of Pediatric Surgery, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Burns : journal of the International Society for Burn Injuries
|November 19, 2023
概括
儿童烧伤感染很常见,但很少有细菌对预防性抗生素敏感. 这凸显了治疗儿科烧伤患者时需要更新抗生素策略的必要性.
科学领域:
- 儿科外科手术 儿科外科手术
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 感染仍然是全球烧伤患者死亡和疾病的主要原因.
- 在儿科烧伤中早期发现细菌殖民者对于有效治疗和预防感染至关重要.
研究的目的:
- 为了研究儿科烧伤中早期的细菌殖民者.
- 为了确定这些分离物的抗生素敏感性.
- 分析轻微和中度烧伤病例对感染率和患者结局的影响.
主要方法:
- 对2009年至2018年期间入院的小至中度烧伤的儿科患者进行了回顾性分析.
- 分析了伤口培养物,以检测细菌的存在和物种识别.
- 对隔离的微生物进行了抗生素敏感性测试.
主要成果:
- 79%的患者在入院时具有阳性伤口培养,其中最常见的是格拉姆阳性细菌.
- 只有35.2%的分离细菌对预防性抗生素敏感,在严重感染的情况下,敏感性降至17%.
- 在最初殖民的患者与负面伤口样本 (p=0.008) 之间观察到住院时间的统计学上显著差异.
结论:
- 细菌殖民在儿科烧伤中很常见,但临床上显著的感染较少 (~10%).
- 观察到对预防性抗生素的低敏感率,表明需要修订治疗方案.
- 这项研究强调了为儿科烧伤患者量身定制的抗生素方法的重要性,以改善结果.
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