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Updated: Jul 10, 2025

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使用AlphaFold2-RAVE探索Kinase Asp-Phe-Gly (DFG) 循环的形态稳定性

Bodhi P Vani1, Akashnathan Aranganathan2, Pratyush Tiwary3

  • 1Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, United States.

Journal of chemical information and modeling
|November 20, 2023
PubMed
概括

AlphaFold2-RAVE增强了用于药物设计的蛋白质动力学模拟. 这种方法准确地预测了酶的结构稳定性变化,有助于开发向癌症疗法.

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