沉积效应在板状触感旋转不对称的折射多焦眼内透镜上,具有+1.5D的额外功率
Takashi Matsushima1, Kenji Kawai
1Department of Ophthalmology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. 313550@cc.u-tokai.ac.jp.
The Tokai journal of experimental and clinical medicine
|November 20, 2023
概括
在眼中的LS-313 MF15多焦眼内眼镜 (IOL) 上形成的沉积物,降低了光学性能. 需要进一步验证LS-313 MF15 IOL的长期稳定性.
科学领域:
- 眼科医生 眼科 眼科
- 生物材料科学 生物材料科学
- 光学工程是指光学工程.
背景情况:
- 眼内透镜 (IOL) 在白内障手术后恢复视力至关重要.
- 多焦内膜眼镜在不同距离提供了更好的视力敏度.
- 了解IOL材料相互作用和长期稳定性对于临床成功至关重要.
研究的目的:
- 为了评估特定多焦内膜眼镜的光学性能和生物相容性.
- 为了研究IOL表面沉积的可能性.
- 为了评估材料特性对体内内膜的 in vivo 性能的影响.
主要方法:
- 在子眼中植入了五种不同水分含量的多焦内射眼镜.
- 细胞增殖和表面沉积物使用裂纹灯生物显微镜进行了检查.
- 表面沉积物被阿里沙林红色染色,并测量了IOL透射率.
- 在IOL储存溶液中的存在通过感应合的等离子体质谱学得到证实.
主要成果:
- 所有植入的IOL都显示细胞增殖.
- 在LS-313 MF15 IOL上观察到明显的颗粒沉积物,确认为.
- 这些沉积物随着时间的推移而增加,并且与IOL透射率下降相关.
- 在所有IOL的储存溶液中检测到,但沉积物是特定于LS-313 MF15.
结论:
- LS-313 MF15 IOL 显示对沉积的敏感性,影响光学传导率.
- 这些发现有助于预测IOL沉积,并为长期稳定性选择材料.
- 建议对LS-313 MF15 IOL进行进一步的临床评估,以确保长期的安全性和有效性.
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