童年创伤后代谢综合征:9年的纵向分析
Camille Souama1,2, Yuri Milaneschi1,2,3,4, Femke Lamers1,2
1Department of Psychiatry, Amsterdam UMC, location Vrije Universiteit Amsterdam, Boelelaan 1117, Amsterdam, The Netherlands.
Psychological medicine
|November 20, 2023
概括
儿童创伤 (CT) 与9年多的成年人持续的代谢健康状况不佳有关. 早期干预和对心脏代谢性疾病风险的监测建议对于有CT病史的人来说.
科学领域:
- 精神病学和临床心理学
- 代谢健康和内分泌学
- 公共卫生和流行病学
背景情况:
- 童年创伤 (CT) 是代谢综合征 (MetS) 的已知危险因素.
- 关于CT对MetS组件的长期影响的纵向数据很少.
- 这项研究旨在纵向调查CT与MetS组件9年进展之间的关联.
研究的目的:
- 在9年的时间内检查童年创伤 (CT) 和代谢综合征 (MetS) 组件之间的纵向关联.
- 确定CT是否影响心脏代谢风险因素的发展和持续.
- 确定童年虐待对代谢健康的潜在长期健康后果.
主要方法:
- 利用了来自荷兰研究抑郁和焦虑队列 (N=2958) 的数据,在9年内进行了四次评估.
- 以后评估CT,包括情绪疏忽和各种形式的虐待.
- 采用混合效应模型来分析CT和连续/分类MetS组件之间的纵向关联,调整社会人口统计学和生活方式因素.
主要成果:
- 近一半 (49%) 的参与者报告CT.
- CT显著与不良代谢结果相关:腰围增加,葡萄糖水平和MetS组件的数量增加.
- 图像扫描也与降低高密度胆固醇和静脉压有关,其影响主要是由严重的图像扫描驱动的,并且独立于生活方式因素.
结论:
- 与没有创伤的成年人相比,有CT病史的成年人随着时间的推移持续表现出较差的代谢健康.
- 患有CT的人面临心脏代谢疾病的风险增加.
- 监测代谢健康和实施早期干预对于CT患者来说至关重要,以减轻长期风险.
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