伊拉克患有状细胞病患者的静音脑梗塞
Noor W Rashid1, Nasir Al-Allawi2, Hamdy I Tahir3
1Department of Hematology, Azadi Teaching Hospital, Duhok, Iraq.
Hemoglobin
|November 20, 2023
概括
在伊拉克状细胞病 (SCD) 患者中,沉默性脑梗塞比以前报告的更少. 这项研究对52名SCD患者进行了查,发现这些神经异常的患病率为11.5%.
科学领域:
- 神经学 神经学
- 血液学 血液学 血液学
- 放射学 放射学是一门学科.
背景情况:
- 沉默性缺血性心脏病发作是全球状细胞病 (SCD) 中常见的神经问题.
- 之前的研究并没有专门研究伊拉克SCD患者的这些心脏病发作.
研究的目的:
- 确定在伊拉克患有状细胞病的患者中沉默性脑梗塞的频率.
- 为了确定潜在的临床或实验室因素,与此群体的静音心脏病发作相关.
主要方法:
- 52名伊拉克SCD患者的队列接受了临床评估和医疗记录的审查.
- 实验室检测包括完整血细胞计数,网状细胞计数,血红蛋白F,乳酸脱酶和胆红素.
- 大脑磁共振成像 (MRI) 用于检测静音脑梗塞.
主要成果:
- 在52名患者中,有6名 (11.5%) 患有无声性脑梗塞,主要发生在深白质中.
- 在患有心脏病发作和没有心脏病发作的患者之间,没有观察到年龄,性别或SCD基因型的显著差异.
- 患有心脏病发作的患者表现出非显著的趋势,即血红蛋白降低,网状细胞增加,疼痛发作减少.
结论:
- 伊拉克SCD患者中无声性脑梗塞的患病率似乎比其他人口更低.
- 对遗传因素的进一步研究可能会阐明这种观察到的较低率的原因.
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