二氧化聚乙烯:来自tris ((hydroxymethyl) phosphine的小型化
James D Nobbs1, Dillon Wei Peng Tay1, Yoon Hui Yeap1
1Institute of Sustainability for Chemicals, Energy and Environment (ISCE2), Agency for Science, Technology and Research (A*STAR), 1 Pesek Road, Jurong Island, Singapore 627833, Republic of Singapore. james_nobbs@isce2.a-star.edu.sg.
Dalton transactions (Cambridge, England : 2003)
|November 20, 2023
概括
新的二氧化 (L1-L4) 连接物被合成并测试在催化水合形成和催化苏苏基-米亚乌拉合,显示出有前途的活性和选择性.
科学领域:
- 有机金属化学 有机金属化学
- 催化剂是一种催化剂.
- 连接体设计 连接体设计
背景情况:
- 二氧化 (dioxaphosphabicyclo[2.2.2]octanes) 是一种新型的子氨酸连接体.
- 这些连接体具有独特的固态和电子特性.
- 它们在催化中的应用尚未得到充分研究.
研究的目的:
- 为了合成新型的二氧化 (dioxaphosphabicyclo) [2.2.2] 八度联体 (L1-L4).
- 为了研究它们与和的协调化学.
- 为了评估它们在甲基和木-米亚乌拉合反应中的催化性能.
主要方法:
- 来自酸和α,β-不和酸的联体的单合成.
- 与前体 ([Rh(acac) ((CO) 2) 和[Rh(CO) 2Cl]2) 的复合.
- 催化试验在介导的甲基化中,对1 octene和介导的苏子基-米亚乌拉合进行催化试验.
主要成果:
- 成功合成和表征了L1-L4联体.
- 形成了复合物[Rh ((acac) ((CO) ((L1)) ]和[Rh ((CO) ((L1) 2Cl],显示了与PPh3类似物相似的CO拉伸频率.
- 在水基甲基化中,配体提供了68%的线性选择性,活性随着硬质散体增加了三倍.
- 形成了复合体,并且[Pd(L1)4]催化了木-米亚乌拉合,产生了适度的产品量.
结论:
- 二氧化 (dioxaphosphabicyclo[2.2.2]octanes) 是和催化物的有效连接物.
- 体体质量显著影响甲基化活性.
- 这些体氨酸为催化应用提供了一个可调节的平台.
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