卡拉使用者的心血管健康;一个叙事审查
Fatemeh Chichagi1,2, Reyhaneh Alikhani2, Asghar Beigi Harchegani3
1Cardiac Primary Prevention Research Center, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
在全球范围内,Kratom (Mitragyna speciosa) 的使用量正在增加. 虽然它可以提供疼痛缓解,但本次审查强调了潜在的心血管风险,包括心动减速和高血压,需要进一步研究.
科学领域:
- 药理学 药理学是指药理学的学科.
- 心脏病学 心脏病学
- 民族植物学 民族植物学
背景情况:
- Kratom (Mitragyna speciosa) 是一个东南亚植物,具有独特的药理特性.
- 它以茶或粉末的形式消费,由于其缓解疼痛的作用,其在全球的流行率正在增加.
- 米特拉金因是 kratom 中的主要活性化合物.
研究的目的:
- 为了全面审查mitragynine的心血管影响.
- 评估与kratom和mitragynine使用相关的潜在心脏毒性.
主要方法:
- 在PubMed,Scopus和谷歌学者中进行文献搜索.
- 包括通过系统性搜索策略确定的所有相关研究.
主要成果:
- 在某些情况下,Kratom使用与多器官损伤和心脏毒性有关.
- 常见的心血管不良影响包括心动减速和高血压.
- 其他潜在的副作用包括动脉样硬化,心律失常,心肌病,QTc延长,心肌炎,心壮症和心肺骤停.
结论:
- 过量服用米特拉基宁可能会对心血管系统产生负面影响.
- 目前的证据是不确定的,强调需要进一步研究Kratom的心血管安全性.
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