全球睡眠质量与冠状动脉微血管功能在职业倦怠的男性医生之间的关联
Roland von Känel1, Mary Princip, Sarah A Holzgang
1From the Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine (von Känel, Princip, Holzgang, Zuccarella-Hackl, Pazhenkottil), Cardiac Imaging, Department of Nuclear Medicine (Rossi, Giannopoulos, Buechel, Pazhenkottil), and Department of Cardiology (Pazhenkottil), University Hospital Zurich, University of Zurich, Zurich, Switzerland.
男性医生的职业倦怠和睡眠质量差与冠状动脉微血管功能的降低有关. 这表明倦怠如何影响心脏健康的途径,特别是影响内皮依赖功能.
科学领域:
- 心脏病学 心脏病学
- 职业健康 职业健康 职业健康
- 睡眠医学 睡眠医学
背景情况:
- 职业倦怠是冠心病的已知危险因素,但潜在的机制尚不清楚.
- 男医生是一个高患倦怠率的专业群体,因此风险增加.
研究的目的:
- 调查全球睡眠质量差与患有燃烧症的男性医生冠状动脉微血管功能受损之间的关联.
- 探索将职业倦怠与心血管疾病联系在一起的潜在机制.
主要方法:
- 一项涉及30名男性医生患有倦怠和30名对照者的研究,使用Maslach Burnout Inventory进行评估.
- 全球睡眠质量使用匹兹堡睡眠质量指数 (PSQI) 进行评估.
- 在寒冷压力测试和腺挑战期间,使用心肌 perfusion 定子发射断层扫描 (PET) 测量冠状动脉微血管功能.
主要成果:
- 睡眠不良 (PSQI评分>5) 在倦怠组 (40%) 比对照组 (10%) 更普遍.
- 倦怠与全球睡眠质量相互作用,对静止心肌血流 (MBF),内皮依赖的冠状动脉流量储备和高血压的MBF产生负面影响.
- 全球PSQI得分显示,与对照组相比,在倦怠组中,与这些MBF措施的反向关联.
结论:
- 全球睡眠质量差与男性医生职业倦怠的内皮依赖冠状动脉微血管功能的降低有关.
- 这一发现表明潜在的机制,通过燃烧导致心血管风险.
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