1-L聚乙烯甘醇 + 甲酸与硫酸 + 酸肠道制剂对结肠镜检查:有效性和安全性
Elena Pérez Arellano1, M ª Isabel Rodríguez García1, Ana Belén Galera Ródenas1
1Gastroenterology, Hospital Universitario La Zarzuela, Spain.
Revista espanola de enfermedades digestivas
|November 20, 2023
概括
低容量聚乙烯甘醇与酸 (1-L PEG + ASC) 提供优越的肠道清洁与酸 (SPMC) 的硫酸相比. 这种方案可以为所有患者获得高质量的结果,无论性别或年龄.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 结肠直肠癌查 结肠直肠癌查
背景情况:
- 适当的肠道准备对于结肠镜的有效性至关重要.
- 聚乙烯甘醇 (PEG) 和皮硫酸盐与酸 (SPMC) 是常见的疗法.
- 在现实环境中,低体积的PEG + 亚酸 (1-L PEG + ASC) 尚未与SPMC进行比较.
研究的目的:
- 为了比较1-L PEG + ASC与SPMC的有效性和安全性.
- 为了评估一般人群,老年患者 (≥65岁) 和按性别的结果.
- 用波士顿肠道制备量表 (BBPS) 评估肠道清洁的质量.
主要方法:
- 随机分配门诊患者到1-L PEG + ASC或SPMC.
- 主要终点:整体和右结肠清洁成功,高质量 (HQ) 清洁.
- 二级终点:根据年龄和性别的有效性和安全性.
主要成果:
- 1-L PEG + ASC 显示肠道清洗成功明显比SPMC更好.
- 在1-L PEG + ASC中,HQ清洗率明显高 (55.5%对25.4%的整体).
- 1-L PEG + ASC在不同性别中同样有效,与SPMC不同,男性的结果更差. 年龄没有影响清洁. 耐受性有所不同,但不影响清洗质量.
结论:
- 1-L PEG + ASC在现实环境中与SPMC相比,提供更高的充足性和HQ肠道清洁.
- 通过1-L PEG + ASC可以实现出色的清洁质量,无论性别或耐受性如何.
- 这种方案提供了一个更一致,更有效的肠道准备选项.
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