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Updated: Jul 10, 2025

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临床结果评估的有意义的患者内部变化:基于模型的方法与累积分布函数相比

Jinma Ren1, Andrew G Bushmakin2, Paul R Cislo3

  • 1Statistical Research & Data Science Center, Pfizer Inc, Collegeville, Pennsylvania, USA.

Journal of biopharmaceutical statistics
|November 20, 2023
PubMed
概括

基于模型的方法在临床结果评估 (COA) 中为有意义的患者内变化 (MWPC) 提供了比实证累积分布函数 (eCDF) 曲线更精确的估计. 这是因为它们整合了更多多样化的COA和得分信息.

关键词:
有意义的患者内部变化.在基的基上.临床结果评估临床结果评估经验累积分布函数的经验累积分布函数.患者报告的结果.

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