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年轻成年期折射误差的变化:纵向屏幕时间,眼睛阳光照射和遗传倾向的影响
Samantha Sze-Yee Lee1,2, Gareth Lingham1,3,4, Carol A Wang5,6,7
1Centre for Ophthalmology and Visual Science (incorporating the Lions Eye Institute), the University of Western Australia, Perth, Western Australia, Australia.
Investigative ophthalmology & visual science
|November 20, 2023
概括
增加屏幕时间,减少阳光照射和遗传因素有助于年轻人近视的进展. 这些因素独立地影响折射误差的变化,尽管可能存在其他驱动因素.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 遗传学 是一个
- 环境健康 环境健康
背景情况:
- 年轻成年期的折射误差变化很常见,但研究不足.
- 这一年龄组近视进展的危险因素需要进一步调查.
研究的目的:
- 探索年轻成年人中折射误差变化的风险因素.
- 调查影响近视进展的基因环境相互作用.
主要方法:
- 测量了20-28岁的624名成年人的球体等效折射率 (SER) 和轴长 (AL).
- 采集了关于屏幕时间的前性数据,并使用结膜紫外线自光学 (CUVAF) 量化了过去的阳光照射.
- 计算了折射误差的多基因分数 (PGS) 和分析了屏幕时间的轨迹.
主要成果:
- 较高的总或电脑屏幕时间,较低的CUVAF和较高的PGS与近视转移的增加有关.
- 与低屏幕时间相比,在持续高或非常高的屏幕时间的人中,近视转移的速度更快.
- 每个z-score增加的PGS与SER的每年变化为-0.005D和AL的每年变化为0.002mm相关.
结论:
- 增加屏幕时间,减少阳光照射和遗传倾向是年轻成年人近视进展的独立风险因素.
- 这些已识别的因素共同解释了折射误差变化偏差的有限部分.
- 需要进一步的研究,以确定影响青春期折射误差发展的其他因素.
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