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Updated: Jul 10, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Published on: March 2, 2014

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复制病毒基因组诱导细胞应激反应,干扰病毒蛋白质表达,而不影响抗病毒免疫力

Lavinia J González Aparicio1, Yanling Yang1, Matthew Hackbart1

  • 1Department of Molecular Microbiology and Center for Women Infectious Disease Research, Washington University School of Medicine in St. Louis, Missouri, United States of America.

PLoS biology
|November 20, 2023
PubMed
概括

回复病毒基因组 (cbVGs) 通过PKR触发压力颗粒 (SG) 形成和翻译抑制,减少病毒蛋白表达,独立于病毒感染期间的MAVS信号. 这种细胞应激反应对于全球抗病毒免疫是不可或缺的.

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