通过可穿戴设备测量心率变化,作为风疾病严重程度的标志物
Ho Bich Hai1, Jonathan W S Cattrall1,2, Nguyen Van Hao3,4
1Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
The American journal of tropical medicine and hygiene
|November 20, 2023
概括
心率变化 (HRV) 可以预测破伤风的严重程度. 可穿戴设备收集了HRV数据,显示它与疾病严重程度和特定的临床指标 (如肌肉和呼吸道损害) 相反相关.
科学领域:
- 临床医学 临床医学
- 生物医学工程 生物医学工程
- 心脏病学 心脏病学
背景情况:
- 结核病具有显著的发病率和死亡率.
- 心率变化 (HRV) 提供了一个潜在的客观标志物,用于评估破伤风的严重程度.
- 可穿戴技术为持续的生理监测提供了机会.
研究的目的:
- 评价可穿戴设备在收集结患者HRV数据中的实用性.
- 为了确定HRV指数和结病的临床严重程度之间的关系.
- 在资源有限的环境中探索HRV作为潜在的生物标志物.
主要方法:
- 使用可穿戴设备收集了来自越南110名ICU患者的24小时心电图 (ECG) 记录.
- 从5分钟的心电图段计算出各种HRV指数.
- 与临床严重性标志物相关的HRV指数,包括肌肉,呼吸损害和自主功能障碍.
主要成果:
- HRV与破伤风的严重程度有相反的关系.
- 具体的HRV指数与临床表现有显著的相关性:NN间标准偏差和肌肉的IRRR;呼吸损害的LF和HF;以及自主功能障碍的几个指数.
结论:
- 通过可穿戴设备测量的HRV显示出有希望作为评估破伤风严重程度的有价值的客观标志物.
- 这种方法在资源有限的环境中是可行的,并且可能具有影响力,在这种环境中破伤风是普遍存在的.
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