EGFR-TKIMYC

GuoSheng Wang1, Tao Li2, Yuan Wan3

  • 1Department of Pulmonary and Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China; The Pq Laboratory of Micro/Nano BiomeDx, Department of Biomedical Engineering, Binghamton University-SUNY, Binghamton, NY 13902, United States.

概括

这项研究揭示了MYC表达与EGFR-TKI耐药性免疫细胞功能之间的反向联系. 损坏的MYC和T细胞中的脂肪酸氧化表明使用MYC抑制剂需要谨慎.

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