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Updated: Jul 10, 2025

Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
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通过I开关I的酸化通过Toxoplasma gondii对Irgb6无活化的结构基础

Hiromichi Okuma1, Yumiko Saijo-Hamano1, Hiroshi Yamada2

  • 1Division of Structural Medicine and Anatomy, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan.

Genes to cells : devoted to molecular & cellular mechanisms
|November 20, 2023
PubMed
概括

在Thr95中对Irgb6的酸化会在Toxoplasma gondii感染期间使这种免疫蛋白失活. 这一发现揭示了一种新的全性机制,控制了细胞对寄生虫的自主免疫力.

关键词:
这是Irgb6的.这种毒性淋巴细胞 (Toxoplasma gondii) 是一个全osteric 形状的变化.与免疫相关的GTPase.酸化的方法是:光化.在X射线晶体学研究中,

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