慢性激素治疗对心血管的影响:对奥运会女运动员的研究
Giuseppe Di Gioia1, Simone Pasquale Crispino2, Viviana Maestrini3
1Institute of Sport Medicine and Science, National Italian Olympic Committee, Largo Piero Gabrielli, Italy; Department of Cardiovascular Sciences, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, Italy; Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro de Bosis, Italy.
女运动员的激素治疗 (HT) 与心脏重塑减少和运动引起的心律失常减少有关. 这表明心脏更有效地适应强度训练,保持心脏功能.
科学领域:
- 心血管生理学心血管生理学
- 运动医学 运动医学
- 内分泌学 在内分泌学.
背景情况:
- 女运动员经历月经周期的荷尔蒙波动,影响心血管功能.
- 女性运动员激素治疗 (HT) 对心血管的影响的数据有限.
- 了解HT的影响对于优化精英女运动员的健康和表现至关重要.
研究的目的:
- 为了研究慢性激素治疗 (HT) 在训练有素的女性运动员身上对心血管的影响.
- 评估HT使用者与非使用者之间心脏改造,运动能力和临床相关的差异.
- 为了确定HT是否影响心脏适应密集体育训练.
主要方法:
- 研究包括380名精英女运动员 (平均年龄25.5±4.8),其中67人 (18%) 患有慢性HT.
- 评估包括心电图,运动压力测试,胸前心电图和综合血液测试.
- 使用统计分析,包括线性回归来确定HT的独立影响.
主要成果:
- 与对照组相比,HT运动员的左心室 (LV) 质量指数,终端透气直径和体积显著降低.
- 在心功能或心放松/填充指数中没有发现显著差异.
- 在HT组中,运动诱导的腹腔失常发病率较低 (1.5%与8.6%相比).
结论:
- 女运动员的慢性激素治疗与良好的心脏重塑 (减少 LV 尺寸和质量) 和保持心脏功能有关.
- 使用HT与减轻运动诱导的心室节律失常的负担相关.
- 在女性运动员中,激素治疗可能会促进更经济但同样有效的心脏适应密集训练.
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