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与初级双胞胎相比,减少多胎妊娠后双胞胎的出生结果

Eline Meireson¹, Laura De Rycke², Esmée M Bijnens³

¹Department of Human Structure and Repair, Ghent University, Ghent, Belgium (Ms Meireson and Dr Roelens); Department of Obstetrics and Gynaecology, Ghent University Hospital, Ghent, Belgium (Ms Meireson and Drs De Rycke, Dehaene, Derom, and Roelens).

American journal of obstetrics & gynecology MFM

|November 20, 2023

概括

减少从三胞胎到双胞胎的多胎妊娠改善了与继续三胞胎相比,妊娠年龄和出生体重等出生结果. 然而,减少三胞胎的结果仍然比32周怀孕前自发双胞胎更糟糕.

科学领域:

生殖医学生殖医学
孕产妇和胎儿医学孕产妇和胎儿医学
周围生理学周围生理学

背景情况:

辅助生殖技术和增加的母亲年龄导致了更多的多胎妊娠.
多重怀孕,特别是高阶怀孕,对母亲和孩子都有很大的风险.
多胎妊娠减少 (MPR) 选择性地减少胎儿数量,以改善剩余胎儿的结果.

研究的目的:

为了比较降低到双胞胎的三子双胞胎与继续三子双胞胎的出生结果.
为了比较减少三胞胎与初级二二双胞胎的出生结果.

主要方法:

使用东弗兰德斯前双胞胎调查 (1990-2016) 数据进行的回顾性队列研究.
相比之下,85例三子妊娠减少到双胞胎,5093例初级二子双胞胎怀孕和104例预期管理的三子怀孕.
评估结果包括分娩时的妊娠年龄,出生体重和对于妊娠年龄的小 (SGA).

主要成果:

从三胞胎到双胞胎的MPR导致与持续三胞胎相比,出生体重和妊娠年龄显著增加.
与持续三胞胎相比,MPR降低的三胞胎显示出SGA风险较低的趋势.
与初级双胞胎相比,减少的三胞胎的出生体重和妊娠年龄较低,在怀孕32周后没有显著差异.

结论:

从三三胞胎到双胞胎的MPR显著改善了分娩结果,使其在医学上得到证明.
虽然MPR改善了结果,但在32周之前出生的初级双胞胎仍然比减少的三胞胎有更好的结果.
预防更高阶怀孕是可取的,因为MPR本质上涉及胎儿损失.

关键词:

出生时的体重出生时的体重.怀孕年龄怀孕年龄减少多胎妊娠,减少多胎妊娠对于怀孕年龄来说小.这是一对三胞胎三胞胎.他们是双胞胎,双胞胎.

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